MHC molecules

MHC Class I molecules are on ALL nucleated cells
MHC Class II molecules are on B cells, monocytes, dendritic cells, and are inducible on keratinocytes and endothelial cells.

TH relation of skin diseases

TH1: psoriasis, contact dermatitis, tuberculoid leprosy
TH2: atopic dermatitis, lepromatous leprosy, SLE

TH1:IL1, IL2, IL12, IL15, IL18, IL23, IFN alpha, IFN gamma, TNF alpha, TNF beta
TH2:IL4, IL5, IL6, IL9, IL10, IL13

Sutures

Absorbable: Catgut, Vicryl, Maxon, Monocryl, PDS, Dexon

Non-absorbable: Polypropylene, Nylon, Navafil, Silk

Waardenburg's syndrome gene

"pack your mittens and pack your socks"

PAX-3
MITF
SOX10

POEMS syndrome

Polyneuropathy
Organomegaly
Endocrinopathy
Monoclonal gammopathy
Skin lesions - gromeruloid hemangioma

DFSP VS Dermatofibroma

Immunohistochemistry staining

Dermatofibrosarcoma protuberans : CD34+++ Factor XIIIa +
Dermatofibroma : CD34+ Factor XIIIa+++

Acute sarcoidosis

LöfgreN syndrome
Hilar Lympadenopathy, erythema Nodosum, fever, migrating polyarthritis, acute iritis

Heerfordt syndrome
Parotid gland enlargement, fever, uveitis, and cranial (usually facial) nerve palsies